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Le modafinil, ou 2-((diphГ©nylmГ©thyl)amino)phГ©nol, est une forme structurellement modifiГ©e de cafГ©ine. En raison de la perception commune selon laquelle le Modafinil crГ©e une dГ©pendance, sa lГ©gitimitГ© en tant qu'alternative plus sГ»re est discutable. C'Г©tait le centre d'une grande partie de la littГ©rature scientifique jusqu'Г la sortie du mГ©dicament dans le courant lГ©gal du commerce en 1998. Dans son article de 2018, le groupe a dГ©crit ce qu'il avait dГ©couvert lors d'un essai antГ©rieur : L'analyse de plusieurs mesures cognitives a rГ©vГ©lГ© que le modafinil amГ©liore l'attention soutenue et les performances de la mГ©moire de travail chez les jeunes adultes en bonne santГ©, mais peut altГ©rer la vigilance et le contrГґle inhibiteur. Un WEEA est un agent pharmacologique qui amГ©liore l'Г©veil de maniГЁre rapide. Le modafinil a ensuite Г©tГ© Г©valuГ© dans un groupe de patients souffrant d'apnГ©e du sommeil.
Modalert Canada La cible du modafinil dans le SNC est les transporteurs de la dopamine. et Alertec. Le modafinil, ou 2-benzylpyrrolidin-3-one (N-0512), a Г©tГ© synthГ©tisГ© pour la premiГЁre fois au dГ©but des annГ©es 1970 en tant qu'isomГЁre Г©rythro du composГ© lГ©vodopa (L-3,4-dihydroxyphГ©nylalanine), mais, comme la lГ©vodopa, il a induit une dГ©plГ©tion de la tyrosine dans le cerveau du rat. Il est disponible sous diffГ©rentes marques telles que Provigil, Relafen et Afinil. Cela conduit Г une augmentation des concentrations de dopamine dans les zones du cerveau associГ©es Г l'Г©veil. Chaque pilule contient 10 mg de mГ©dicament. Le modafinil peut ГЄtre utilisГ© chez les personnes atteintes de narcolepsie, ainsi que de troubles du sommeil liГ©s au travail postГ© et d'apnГ©e obstructive du sommeil.
Nootropiques En Vente Libre Les mГ©dicaments contenant du modafinil peuvent ne pas ГЄtre sГ»rs chez les personnes souffrant de problГЁmes cardiaques, d'Г©pilepsie ou d'une maladie du foie. Il convient donc de faire preuve de prudence chez ces patients. Plusieurs lignes directrices recommandent son utilisation pour les personnes souffrant d'apnГ©e du sommeil. Ceux-ci incluent l'Гўge de l'individu, la dose de modafinil qu'il prend actuellement et sa tolГ©rance aux effets secondaires. L'Г©tude n'a pas trouvГ© de diffГ©rences significatives entre les effets du mГ©dicament sur les hommes et les femmes, et n'a trouvГ© aucune diffГ©rence entre les participants qui avaient pris le mГ©dicament pendant moins de six semaines et ceux qui l'avaient pris pendant plus de six mois. Les neurones dopaminergiques sont prГ©sents dans l'hypothalamus et l'hypophyse. Les pilules de 200 mg contiennent une formulation lГ©gГЁrement diffГ©rente du mГ©dicament.
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